A Phase 2a dose-escalation study of the safety, tolerability, pharmacokinetics and hemodynamic effects of BMS-986231 in hospitalized patients with heart failure with reduced ejection fraction
Authors: Cristina Tita , Edward M Gilbert , Adrian B Van Bakel , Jacek Grzybowski , Garrie J Haas , Mohammad Jarrah , Stephanie H Dunlap , Stephen S Gottlieb , Marc Klapholz , Parag C Patel , Roman Pfister , Tim Seidler , Keyur B Shah , Tomasz Zieliński , Robert P Venuti , […]
Continuous non-invasive measurement of stroke volume and cardiac index in infants and children: comparison of Impedance Cardiography NICaS vs CardioQ method
Authors: R Beck 1, L Milella 2, C Labellarte 3 Conclusion: Good correlation was observed in pediatric patients for CI measured with NICaS® in comparison with CardioQ® device. Continuous non-invasive monitoring of NI-CI can be particularly interesting for the pediatric population. For the full article click here
Validation of Non-invasive Cardiac System (NICaS) Derived Stroke Volume With Cardiac Magnetic Resonance
Authors: Pedram Hassan-Tash, Umar Ismail, Gurkirat Chana, Iain Kirkpatrick, Davinder S Jassal, Brett Hiebert, Amir Ravandi, Malek Kass, Ashish H Shah Conclusion: Stroke volume measured using NICaS strongly correlated with that from CMR. NICaS also demonstrated strong consistency in SV derived at different time points in the same individual. For the full article click here
Whole-body electrical bio-impendance is accurate in non invasive determination of cardiac output: A thermodilution controlled, prospective, double blind evaluation.
Authors: Guillermo Torre-Amione, Olga Milo, Edo Kaluski, Zvi Vered, Gad Cotter NICaS is a novel accurate noninvasive method for CO determination. The results of this study suggest that the NICaS might be more accurate than thermodilution for CO determination due to the tendency of thermodilution to underestimate CO when high and overestimate it when low. […]
Perioperative sequential monitoring of hemodynamic parameters in patients with pheochromocytoma using the NICaS
Authors: Yayoi Matsuda, Hisaya Kawate, Shingo Shimada, Chitose Matsuzaki, Hiromi Nagata, Masahiro Adachi, Keizo Ohnaka, Masatoshi Nomura, Ryoichi Takayanagi Conclusion: The results of this study show the potential usefulness of sequential monitoring of hemodynamic status using NICaS in patients with pheochromocytoma during the perioperative period. Despite some limitations, NICaS-derived CO seems to be applicable to […]
Non-invasive measurement of cardiac output by whole-body bio-impedance during dobutamine stress echocardiography: Clinical implications in patients with left ventricular dysfunction and ischemia
Authors: Gad Cotter, Marina Laitman, Edgar Sucher, Eli Peleg, Edo Kaluski, Ruth Wolf, Zvi Vered Conclusion: Measurement of CI by NICaS correlated well with Doppler-derived CI. The calculation of Cpi and TPRI changes during dobutamine stress may provide important clinical information. For the full article click here
Noninvasive and simple assessment of cardiac output and pulmonary vascular resistance with whole-body impedance cardiography is useful for monitoring patients with pulmonary hypertension
Background: Cardiac Power Index (CPI) is a novel parameter calculated by CI*MAP and is considered to be a reliable indicator of myocardial contractility. Previous studies done by RHC technique demonstrated that CPI is the best in-hospital mortality predictor4,5,6. The target of this study was to find whether non-invasively measured CPI has a good predictive capability […]
Impedance cardiography revisited
Authors: G Cotter1, A Schachner2, L Sasson2, H Dekel2 and Y Moshkovitz3 Conclusion: The present CO results measured by the NICaS device indicate that, with regard to the accuracy of measuring the CO, the RIC technology outperforms any other ICG technology, being twice as accurate as TIC. For the full article click here
Impedance cardiography for cardiac output estimation reliability of wrist-to-ankle electrode configuration
Authors: Oscar Luis Paredes, Junya Shite, Toshiro Shinke, Satoshi Watanabe, Hiromasa Otake, Daisuke Matsumoto, Yusuke Imuro, Daisuke Ogasawara, Takahiro Sawada, Mitsuhiro Yokoyama Conclusion: The present study is aimed to test the effectiveness of the Non-Invasive Cardiac System (NICaS), a new ICG device working with a wrist-to-ankle configuration. The study indicates that NICaS performs at least […]
Comparison of two methods of assessing total body water at sea level and increasing high altitude
Authors: C J Boos , D A Holdsworth, D P Hall, A Mellor, J O’Hara, D R Woods Overview: Assessment of hydration and nutritional status in clinical practice can be challenging and relies on a variety of assessments, the ability to accurately quantify total body water (TBW) and its distribution between intracellular (ICW) and extracellular […]