Detection of left ventricular systolic dysfunction using a newly developed, laptop based, impedance cardiographic index

Yoseph Rozenman , Renee Rotzak , Robert P Patterson

A GGI cutoff of 10 was 89% sensitive and 96% specific for the detection of LVSD, confirming the excellent results of the training set. Positive and negative predictive values were 78% and 98% respectively.
False positives and false negatives of GGI as a predictor of EF are extremely rare reflecting the accuracy of GGI to detect LVSD. Careful observation of the data points suggests that rather than a simple correlation, the relation between EF and GGI is more like a step function with a GGI<10 corresponding to a wide range of EF<55% while a GGI≥10 corresponds to varying levels of EF≥55%.

The GGI can accurately detect LVSD in subjects at risk (referred for echocardiography).

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